Weight Management Capsules (Lipase inhibitors)

Essential information

Lipase inhibitors are prescription medicines that support weight management by reducing the absorption of dietary fat. They act locally in the digestive system, helping to lower overall calorie intake when used alongside a healthy diet and regular physical activity. Our prescribers may consider a lipase inhibitor such as Orlistat or Xenical following a full clinical assessment. These medicines are prescribed only when suitable and are accompanied by clear guidance on diet, lifestyle, and safe use.

Each medicine is prescribed only after a professional consultation to ensure it is safe and appropriate for your individual health needs.

Xenical (orlistat) and generic orlistat

What it is

Lipase inhibitors, such as orlistat, are prescription medicines that reduce the absorption of dietary fat. They are used as part of a weight-management programme alongside lifestyle changes.

How it works

These medicines act locally in the digestive system to block some of the enzymes that break down fat. This helps reduce overall calorie intake from food.

Suitability

Lipase inhibitors may be prescribed for adults with obesity or overweight, particularly when dietary adjustment alone has not achieved sufficient weight reduction. The prescriber will assess suitability based on your medical background.

Consultation and prescribing

Treatment is only initiated following a consultation with a prescriber, who will confirm whether this class of medicine is appropriate for you and provide clear instructions for safe use.

Possible side effects

The most common effects include mild digestive symptoms related to unabsorbed fat. Your prescriber will explain how to manage these effects and monitor your progress.

Lifestyle and support

Lipase inhibitors are most effective when combined with a reduced-fat diet, increased activity, and continued professional support. We’ll help you build these habits as part of your treatment plan.

Prices as of October 2025

Orlistat Capsules 120mg generic

1 box 84 caps: £45.

2 box 168 caps £80.

Prices can be confirmed on request and are subject to occasional revision.

Xenical Capsules 120mg branded

1 box 84 caps: £57.

2 box 168 caps £114.